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KMID : 0384620110220030117
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Korean Journal of Medical Physics
2011 Volume.22 No. 3 p.117 ~ p.123
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Synchrotron Radiation Imaging of Breast Tissue Using a Phase-contrast Hard X-ray Microscope
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Jung Young-Ju
Bong Jin-Gu
Park Sung-Hwan
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Abstract
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Synchrotron radiation (SR) imaging enables us to observe internal structures of biologic samples without staining. In this study, we obtained X-ray microscopic images of human breast tissues with 11.1 KeV hard X-ray microscope of the Pohang light source and used zone plates and phase-contrast technique to get high resolution X-ray images. Hard X-ray microscopic images of fibrocystic change and breast cancer tissues with a spatial resolution of 60 nm were obtained and from these images, we could observe the micro-structures of human breast tissue. Also we analyzed and compared these images, which revealed distinct features of each condition. In conclusion, SR imaging with phase-contrast hard X-ray microscope for medical application, especially in breast disease can give some useful information for clinical research.
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KEYWORD
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Hard X-ray microscopic imaging, Phase-contrast, Synchrotron radiation, Breast imaging
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